diff --git a/docs/content/news.md b/docs/content/news.md
index 0ee83ad3..6315a88c 100644
--- a/docs/content/news.md
+++ b/docs/content/news.md
@@ -1,6 +1,18 @@
 <span id="news"></span>
 # Changelog
 
+## unreleased
+
+### Performance
+
+- **ASGI HTTP Parser Optimizations**: Improve ASGI worker HTTP parsing performance
+  - Read chunks in 64-byte blocks instead of 1 byte at a time for chunk size lines and trailers
+  - Reuse BytesIO buffers with truncate/seek instead of creating new objects (reduces GC pressure)
+  - Use `bytearray.find()` directly instead of converting to bytes first
+  - Use index-based iteration for header parsing instead of `list.pop(0)` (O(1) vs O(n))
+
+---
+
 ## 25.1.0 - 2026-02-13
 
 ### New Features
diff --git a/gunicorn/asgi/message.py b/gunicorn/asgi/message.py
index 73a6e7da..45afb851 100644
--- a/gunicorn/asgi/message.py
+++ b/gunicorn/asgi/message.py
@@ -8,7 +8,6 @@ Async version of gunicorn/http/message.py for ASGI workers.
 Reuses the parsing logic from the sync version, adapted for async I/O.
 """
 
-import io
 import ipaddress
 import re
 import socket
@@ -151,26 +150,23 @@ class AsyncRequest:
 
         self._parse_request_line(line)
 
-        # Headers
-        data = bytes(buf)
-
+        # Headers - use bytearray.find() directly to avoid bytes() conversions
         while True:
-            idx = data.find(b"\r\n\r\n")
-            done = data[:2] == b"\r\n"
+            idx = buf.find(b"\r\n\r\n")
+            done = buf[:2] == b"\r\n"
 
             if idx < 0 and not done:
                 await self._read_into(buf)
-                data = bytes(buf)
-                if len(data) > self.max_buffer_headers:
+                if len(buf) > self.max_buffer_headers:
                     raise LimitRequestHeaders("max buffer headers")
             else:
                 break
 
         if done:
-            self.unreader.unread(data[2:])
+            self.unreader.unread(bytes(buf[2:]))
         else:
-            self.headers = self._parse_headers(data[:idx], from_trailer=False)
-            self.unreader.unread(data[idx + 4:])
+            self.headers = self._parse_headers(bytes(buf[:idx]), from_trailer=False)
+            self.unreader.unread(bytes(buf[idx + 4:]))
 
         self._set_body_reader()
 
@@ -182,21 +178,23 @@ class AsyncRequest:
         buf.extend(data)
 
     async def _read_line(self, buf, limit=0):
-        """Read a line from buffer, returning (line, remaining_buffer)."""
-        data = bytes(buf)
+        """Read a line from buffer, returning (line, remaining_buffer).
 
+        Uses bytearray.find() directly to avoid repeated bytes() conversions.
+        """
         while True:
-            idx = data.find(b"\r\n")
+            idx = buf.find(b"\r\n")
             if idx >= 0:
                 if idx > limit > 0:
                     raise LimitRequestLine(idx, limit)
                 break
-            if len(data) - 2 > limit > 0:
-                raise LimitRequestLine(len(data), limit)
+            if len(buf) - 2 > limit > 0:
+                raise LimitRequestLine(len(buf), limit)
             await self._read_into(buf)
-            data = bytes(buf)
 
-        return (data[:idx], bytearray(data[idx + 2:]))
+        line = bytes(buf[:idx])
+        remaining = bytearray(buf[idx + 2:])
+        return (line, remaining)
 
     async def _handle_proxy_protocol(self, buf, mode):
         """Handle PROXY protocol detection and parsing.
@@ -422,11 +420,16 @@ class AsyncRequest:
                 raise InvalidHTTPVersion(self.version)
 
     def _parse_headers(self, data, from_trailer=False):
-        """Parse HTTP headers from raw data."""
+        """Parse HTTP headers from raw data.
+
+        Uses index-based iteration instead of list.pop(0) for O(1) access.
+        """
         cfg = self.cfg
         headers = []
 
         lines = [bytes_to_str(line) for line in data.split(b"\r\n")]
+        num_lines = len(lines)
+        i = 0
 
         # Handle scheme headers
         scheme_header = False
@@ -440,11 +443,12 @@ class AsyncRequest:
             secure_scheme_headers = cfg.secure_scheme_headers
             forwarder_headers = cfg.forwarder_headers
 
-        while lines:
+        while i < num_lines:
             if len(headers) >= self.limit_request_fields:
                 raise LimitRequestHeaders("limit request headers fields")
 
-            curr = lines.pop(0)
+            curr = lines[i]
+            i += 1
             header_length = len(curr) + len("\r\n")
             if curr.find(":") <= 0:
                 raise InvalidHeader(curr)
@@ -457,11 +461,12 @@ class AsyncRequest:
             name = name.upper()
             value = [value.strip(" \t")]
 
-            # Consume value continuation lines
-            while lines and lines[0].startswith((" ", "\t")):
+            # Consume value continuation lines using index-based iteration
+            while i < num_lines and lines[i].startswith((" ", "\t")):
                 if not self.cfg.permit_obsolete_folding:
                     raise ObsoleteFolding(name)
-                curr = lines.pop(0)
+                curr = lines[i]
+                i += 1
                 header_length += len(curr) + len("\r\n")
                 if header_length > self.limit_request_field_size > 0:
                     raise LimitRequestHeaders("limit request headers fields size")
@@ -676,29 +681,48 @@ class AsyncRequest:
                     raise InvalidHeader("Missing chunk terminator")
 
     async def _read_chunk_size_line(self):
-        """Read a chunk size line."""
-        buf = io.BytesIO()
+        """Read a chunk size line.
+
+        Performance optimization: reads 64-byte chunks instead of 1 byte at a time,
+        then pushes back any excess data after finding the line terminator.
+        """
+        buf = bytearray()
         while True:
-            data = await self.unreader.read(1)
+            data = await self.unreader.read(64)
             if not data:
                 raise NoMoreData()
-            buf.write(data)
-            if buf.getvalue().endswith(b"\r\n"):
-                return buf.getvalue()[:-2]
+            buf.extend(data)
+            idx = buf.find(b"\r\n")
+            if idx >= 0:
+                # Push back any data after the line
+                if idx + 2 < len(buf):
+                    self.unreader.unread(bytes(buf[idx + 2:]))
+                return bytes(buf[:idx])
 
     async def _skip_trailers(self):
-        """Skip trailer headers after chunked body."""
-        buf = io.BytesIO()
+        """Skip trailer headers after chunked body.
+
+        Performance optimization: reads 64-byte chunks instead of 1 byte at a time,
+        then pushes back any excess data after finding the trailer terminator.
+        """
+        buf = bytearray()
         while True:
-            data = await self.unreader.read(1)
+            data = await self.unreader.read(64)
             if not data:
                 return
-            buf.write(data)
-            content = buf.getvalue()
-            if content.endswith(b"\r\n\r\n"):
-                # Could parse trailers here if needed
+            buf.extend(data)
+            # Check for empty trailer (just CRLF)
+            if buf[:2] == b"\r\n":
+                # Push back remaining data
+                if len(buf) > 2:
+                    self.unreader.unread(bytes(buf[2:]))
                 return
-            if content == b"\r\n":
+            # Check for full trailer terminator
+            idx = buf.find(b"\r\n\r\n")
+            if idx >= 0:
+                # Push back data after the trailer
+                if idx + 4 < len(buf):
+                    self.unreader.unread(bytes(buf[idx + 4:]))
                 return
 
     async def drain_body(self):
diff --git a/gunicorn/asgi/unreader.py b/gunicorn/asgi/unreader.py
index c8d9aa82..330f56db 100644
--- a/gunicorn/asgi/unreader.py
+++ b/gunicorn/asgi/unreader.py
@@ -16,6 +16,9 @@ class AsyncUnreader:
 
     This class wraps an asyncio StreamReader and provides the ability
     to "unread" data back into a buffer for re-parsing.
+
+    Performance optimization: Reuses BytesIO buffer with truncate/seek
+    instead of creating new objects to reduce GC pressure.
     """
 
     def __init__(self, reader, max_chunk=8192):
@@ -28,6 +31,25 @@ class AsyncUnreader:
         self.reader = reader
         self.buf = io.BytesIO()
         self.max_chunk = max_chunk
+        self._buf_start = 0  # Start position of valid data in buffer
+
+    def _reset_buffer(self):
+        """Reset buffer for reuse instead of creating new BytesIO."""
+        self.buf.seek(0)
+        self.buf.truncate(0)
+        self._buf_start = 0
+
+    def _get_buffered_data(self):
+        """Get all buffered data and reset buffer."""
+        self.buf.seek(self._buf_start)
+        data = self.buf.read()
+        self._reset_buffer()
+        return data
+
+    def _buffer_size(self):
+        """Get size of buffered data."""
+        end = self.buf.seek(0, io.SEEK_END)
+        return end - self._buf_start
 
     async def read(self, size=None):
         """Read data from the stream, using buffered data first.
@@ -48,31 +70,39 @@ class AsyncUnreader:
             if size < 0:
                 size = None
 
-        # Move to end to check buffer size
-        self.buf.seek(0, io.SEEK_END)
+        buf_size = self._buffer_size()
 
         # If no size specified, return buffered data or read chunk
-        if size is None and self.buf.tell():
-            ret = self.buf.getvalue()
-            self.buf = io.BytesIO()
-            return ret
+        if size is None and buf_size > 0:
+            return self._get_buffered_data()
         if size is None:
             chunk = await self._read_chunk()
             return chunk
 
         # Read until we have enough data
-        while self.buf.tell() < size:
+        while buf_size < size:
             chunk = await self._read_chunk()
             if not chunk:
-                ret = self.buf.getvalue()
-                self.buf = io.BytesIO()
-                return ret
+                return self._get_buffered_data()
+            self.buf.seek(0, io.SEEK_END)
             self.buf.write(chunk)
+            buf_size += len(chunk)
 
-        data = self.buf.getvalue()
-        self.buf = io.BytesIO()
-        self.buf.write(data[size:])
-        return data[:size]
+        # We have enough data - extract what we need
+        self.buf.seek(self._buf_start)
+        data = self.buf.read(size)
+
+        # Update start position instead of creating new buffer
+        self._buf_start += size
+
+        # If buffer is getting large with consumed data, compact it
+        if self._buf_start > 8192:
+            remaining = self.buf.read()  # Read from current position
+            self._reset_buffer()
+            if remaining:
+                self.buf.write(remaining)
+
+        return data
 
     async def _read_chunk(self):
         """Read a chunk of data from the underlying stream."""
@@ -86,15 +116,20 @@ class AsyncUnreader:
 
         Args:
             data: bytes to push back
+
+        Note: This prepends data to the buffer so it will be read first.
         """
         if data:
-            self.buf.seek(0, io.SEEK_END)
+            # Get existing buffered data
+            self.buf.seek(self._buf_start)
+            existing = self.buf.read()
+
+            # Reset and write new data first, then existing
+            self._reset_buffer()
             self.buf.write(data)
+            if existing:
+                self.buf.write(existing)
 
     def has_buffered_data(self):
         """Check if there's data in the pushback buffer."""
-        pos = self.buf.tell()
-        self.buf.seek(0, io.SEEK_END)
-        has_data = self.buf.tell() > 0
-        self.buf.seek(pos)
-        return has_data
+        return self._buffer_size() > 0
diff --git a/tests/test_asgi_parser.py b/tests/test_asgi_parser.py
new file mode 100644
index 00000000..15211798
--- /dev/null
+++ b/tests/test_asgi_parser.py
@@ -0,0 +1,325 @@
+#
+# This file is part of gunicorn released under the MIT license.
+# See the NOTICE for more information.
+
+"""
+Tests for ASGI HTTP parser optimizations.
+"""
+
+import asyncio
+import ipaddress
+import pytest
+
+from gunicorn.asgi.unreader import AsyncUnreader
+from gunicorn.asgi.message import AsyncRequest
+
+
+class MockStreamReader:
+    """Mock asyncio.StreamReader for testing."""
+
+    def __init__(self, data):
+        self.data = data
+        self.pos = 0
+
+    async def read(self, size=-1):
+        if self.pos >= len(self.data):
+            return b""
+        if size < 0:
+            result = self.data[self.pos:]
+            self.pos = len(self.data)
+        else:
+            result = self.data[self.pos:self.pos + size]
+            self.pos += size
+        return result
+
+
+class MockConfig:
+    """Mock gunicorn config for testing."""
+
+    def __init__(self):
+        self.is_ssl = False
+        self.proxy_protocol = "off"
+        self.proxy_allow_ips = ["127.0.0.1"]
+        self.forwarded_allow_ips = ["127.0.0.1"]
+        self._proxy_allow_networks = None
+        self._forwarded_allow_networks = None
+        self.secure_scheme_headers = {}
+        self.forwarder_headers = []
+        self.limit_request_line = 8190
+        self.limit_request_fields = 100
+        self.limit_request_field_size = 8190
+        self.permit_unconventional_http_method = False
+        self.permit_unconventional_http_version = False
+        self.permit_obsolete_folding = False
+        self.casefold_http_method = False
+        self.strip_header_spaces = False
+        self.header_map = "refuse"
+
+    def forwarded_allow_networks(self):
+        if self._forwarded_allow_networks is None:
+            self._forwarded_allow_networks = [
+                ipaddress.ip_network(addr)
+                for addr in self.forwarded_allow_ips
+                if addr != "*"
+            ]
+        return self._forwarded_allow_networks
+
+    def proxy_allow_networks(self):
+        if self._proxy_allow_networks is None:
+            self._proxy_allow_networks = [
+                ipaddress.ip_network(addr)
+                for addr in self.proxy_allow_ips
+                if addr != "*"
+            ]
+        return self._proxy_allow_networks
+
+
+# Optimized Chunk Reading Tests
+
+@pytest.mark.asyncio
+async def test_chunk_size_line_reading():
+    """Test optimized chunk size line reading."""
+    # Simulate chunked body with chunk size line
+    data = b"a\r\nhello body\r\n0\r\n\r\n"
+    reader = MockStreamReader(data)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = AsyncRequest(cfg, unreader, ("127.0.0.1", 8000))
+    # Access the private method for testing
+    line = await req._read_chunk_size_line()
+    assert line == b"a"
+
+
+@pytest.mark.asyncio
+async def test_skip_trailers_empty():
+    """Test skipping empty trailers."""
+    data = b"\r\n"
+    reader = MockStreamReader(data)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = AsyncRequest(cfg, unreader, ("127.0.0.1", 8000))
+    # Should not raise
+    await req._skip_trailers()
+
+
+@pytest.mark.asyncio
+async def test_skip_trailers_with_headers():
+    """Test skipping trailers with actual headers."""
+    data = b"X-Checksum: abc123\r\n\r\n"
+    reader = MockStreamReader(data)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = AsyncRequest(cfg, unreader, ("127.0.0.1", 8000))
+    # Should not raise
+    await req._skip_trailers()
+
+
+# Buffer Reuse Tests
+
+@pytest.mark.asyncio
+async def test_unreader_buffer_reuse():
+    """Test that AsyncUnreader reuses buffers efficiently."""
+    data = b"GET / HTTP/1.1\r\nHost: example.com\r\n\r\n"
+    reader = MockStreamReader(data)
+    unreader = AsyncUnreader(reader)
+
+    # Read in chunks
+    chunk1 = await unreader.read(10)
+    assert chunk1 == b"GET / HTTP"
+
+    # Read more
+    chunk2 = await unreader.read(10)
+    assert chunk2 == b"/1.1\r\nHost"
+
+    # Unread some data
+    unreader.unread(b"/1.1\r\nHost")
+
+    # Read again - should get unreaded data
+    chunk3 = await unreader.read(10)
+    assert chunk3 == b"/1.1\r\nHost"
+
+
+@pytest.mark.asyncio
+async def test_unreader_unread_prepends():
+    """Test that unread prepends data."""
+    data = b"original"
+    reader = MockStreamReader(data)
+    unreader = AsyncUnreader(reader)
+
+    # Read some data first
+    await unreader.read(4)  # "orig"
+
+    # Unread something different
+    unreader.unread(b"NEW")
+
+    # Should read the new data first
+    result = await unreader.read(3)
+    assert result == b"NEW"
+
+
+# Header Parsing Optimization Tests
+
+@pytest.mark.asyncio
+async def test_header_parsing_index_iteration():
+    """Test that header parsing uses index-based iteration."""
+    raw_request = (
+        b"GET / HTTP/1.1\r\n"
+        b"Host: example.com\r\n"
+        b"Content-Type: text/plain\r\n"
+        b"X-Custom: value\r\n"
+        b"\r\n"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert req.method == "GET"
+    assert req.path == "/"
+    assert len(req.headers) == 3
+    assert ("HOST", "example.com") in req.headers
+    assert ("CONTENT-TYPE", "text/plain") in req.headers
+    assert ("X-CUSTOM", "value") in req.headers
+
+
+@pytest.mark.asyncio
+async def test_many_headers_performance():
+    """Test parsing request with many headers."""
+    headers = []
+    for i in range(50):
+        headers.append(f"X-Header-{i}: value-{i}\r\n")
+
+    raw_request = (
+        b"GET / HTTP/1.1\r\n"
+        + "".join(headers).encode()
+        + b"\r\n"
+    )
+
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert len(req.headers) == 50
+
+
+# Bytearray Find Optimization Tests
+
+@pytest.mark.asyncio
+async def test_bytearray_find_optimization():
+    """Test that bytearray.find() is used instead of bytes().find()."""
+    raw_request = (
+        b"GET /path?query=value HTTP/1.1\r\n"
+        b"Host: example.com\r\n"
+        b"Content-Length: 5\r\n"
+        b"\r\n"
+        b"hello"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert req.method == "GET"
+    assert req.path == "/path"
+    assert req.query == "query=value"
+    assert req.content_length == 5
+
+
+# Chunked Body Tests with Optimized Reading
+
+@pytest.mark.asyncio
+async def test_chunked_body_optimized_reading():
+    """Test reading chunked body with optimized chunk reading."""
+    raw_request = (
+        b"POST / HTTP/1.1\r\n"
+        b"Host: example.com\r\n"
+        b"Transfer-Encoding: chunked\r\n"
+        b"\r\n"
+        b"5\r\nhello\r\n"
+        b"6\r\n world\r\n"
+        b"0\r\n\r\n"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert req.chunked is True
+    assert req.content_length is None
+
+    # Read body
+    body_parts = []
+    while True:
+        chunk = await req.read_body(1024)
+        if not chunk:
+            break
+        body_parts.append(chunk)
+
+    body = b"".join(body_parts)
+    assert body == b"hello world"
+
+
+@pytest.mark.asyncio
+async def test_chunked_body_with_extension():
+    """Test reading chunked body with chunk extensions."""
+    raw_request = (
+        b"POST / HTTP/1.1\r\n"
+        b"Host: example.com\r\n"
+        b"Transfer-Encoding: chunked\r\n"
+        b"\r\n"
+        b"5;ext=value\r\nhello\r\n"
+        b"0\r\n\r\n"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    chunk = await req.read_body(1024)
+    assert chunk == b"hello"
+
+
+# Edge Cases
+
+@pytest.mark.asyncio
+async def test_empty_headers():
+    """Test request with no headers."""
+    raw_request = (
+        b"GET / HTTP/1.1\r\n"
+        b"\r\n"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert req.method == "GET"
+    assert len(req.headers) == 0
+
+
+@pytest.mark.asyncio
+async def test_large_header_value():
+    """Test request with large header value."""
+    large_value = "x" * 4000  # Within default limit
+    raw_request = (
+        b"GET / HTTP/1.1\r\n"
+        + f"X-Large-Header: {large_value}\r\n".encode()
+        + b"\r\n"
+    )
+    reader = MockStreamReader(raw_request)
+    unreader = AsyncUnreader(reader)
+    cfg = MockConfig()
+
+    req = await AsyncRequest.parse(cfg, unreader, ("127.0.0.1", 8000))
+
+    assert req.get_header("X-Large-Header") == large_value